Find hotels in Upstate South Carolina, SC from $65
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Go beyond your typical stay in Upstate South Carolina
Pet friendly
Family friendly
Apartment
Apart hotel
Chalet
Waterpark
Cabin
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Check prices for these dates
Tonight
Aug 17 - Aug 18Tomorrow
Aug 18 - Aug 19This weekend
Aug 21 - Aug 23Next weekend
Aug 28 - Aug 30Our top choices for Upstate South Carolina hotels
1. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
Robert
$100 nightly
$111 total
Aug 30 - Aug 31
Total with taxes and fees
2. Drury Inn & Suites Greenville
Drury Inn & Suites GreenvilleGreenville
Gohan
$115 nightly
$126 total
Aug 30 - Aug 31
Total with taxes and fees
3. Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph CollectionGreenville Downtown
David
$361 nightly
$396 total
Sep 7 - Sep 8
Total with taxes and fees
4. Hyatt Regency Greenville
Hyatt Regency GreenvilleGreenville Downtown
Kristina
$157 nightly
$172 total
Sep 6 - Sep 7
Total with taxes and fees
5. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Nancy
$83 nightly
$91 total
Aug 30 - Aug 31
Total with taxes and fees
6. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
Cole
$83 nightly
$91 total
Aug 20 - Aug 21
Total with taxes and fees
7. Hotel Hartness
Hotel HartnessGreenville
Cornelius
$209 nightly
$229 total
Aug 28 - Aug 29
Total with taxes and fees
8. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHGGreenville
Jessica
$90 nightly
$100 total
Sep 3 - Sep 4
Total with taxes and fees
9. Hilton Greenville
Hilton GreenvilleGreenville
Gildardo
$106 nightly
$116 total
Sep 4 - Sep 5
Total with taxes and fees
10. Hyatt Place Greenville Downtown
Hyatt Place Greenville DowntownGreenville Downtown
Melanie
$135 nightly
$148 total
Sep 7 - Sep 8
Total with taxes and fees
11. Aloft by Marriott Greenville Downtown
Aloft by Marriott Greenville DowntownGreenville Downtown
Rebecca
$142 nightly
$157 total
Sep 7 - Sep 8
Total with taxes and fees
12. Hyatt Place Greenville/Haywood
Hyatt Place Greenville/HaywoodGreenville
Yajaira Galilea Cruz
$82 nightly
$91 total
Aug 31 - Sep 1
Total with taxes and fees
13. Embassy Suites by Hilton Greenville Downtown Riverplace
Embassy Suites by Hilton Greenville Downtown RiverplaceGreenville Downtown
LATOYA
$151 nightly
$166 total
Sep 8 - Sep 9
Total with taxes and fees
14. Homewood Suites by Hilton Greenville Downtown
Homewood Suites by Hilton Greenville DowntownGreenville Downtown
Lee
$143 nightly
$157 total
Sep 7 - Sep 8
Total with taxes and fees
15. Hampton Inn & Suites Greenville-Downtown-RiverPlace
Hampton Inn & Suites Greenville-Downtown-RiverPlaceGreenville Downtown
Layne
$154 nightly
$169 total
Sep 3 - Sep 4
Total with taxes and fees
16. The Westin Poinsett Greenville
The Westin Poinsett GreenvilleGreenville Downtown
Andre
$176 nightly
$194 total
Sep 7 - Sep 8
Total with taxes and fees
17. DoubleTree by Hilton Greenville Woodruff Road
DoubleTree by Hilton Greenville Woodruff RoadGreenville
Jennifer
$117 nightly
$129 total
Aug 30 - Aug 31
Total with taxes and fees
18. SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
Douglas
$141 nightly
$155 total
Aug 31 - Sep 1
Total with taxes and fees
19. La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
La Quinta by Wyndham Haywood Mall-Near Greenville DowntownGreenville
Kai
$68 nightly
$75 total
Aug 31 - Sep 1
Total with taxes and fees
20. Baymont by Wyndham Greenville Woodruff Rd
Baymont by Wyndham Greenville Woodruff RdGreenville
Maria V
$65 nightly
$72 total
Aug 30 - Aug 31
Total with taxes and fees
Vacation Rentals in Upstate South Carolina
Aparthotel
stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"All the staff from front desk to housekeeping were excellent, friendly and helpful. If looking for rooms with a feel like home StayApt is what you are looking for. I recommend reserving here great place if you want to cook your own meals"
Apartment
Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"Love the location. Room was great."
Cottage
Claires Cottage ~ 4 Mi to Downtown Greenville!
Claires Cottage ~ 4 Mi to Downtown Greenville!Greenville
"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."
Aparthotel
The Station by Compo Hotels
The Station by Compo HotelsTravelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
Cabin
Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Very relaxing, clean environment. Felt safe and welcoming."
Aparthotel
Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Cottage
Clemson Memorabilia House
Clemson Memorabilia HouseClemson
"We enjoyed our stay, it was the perfect size for our family of four. "
Mobile Home
Carolina Landing RV Resort - Caravan Park
Carolina Landing RV Resort - Caravan ParkFair Play
"Very nice stay with friendly staff"
Cottage
2 Mi to Downtown: Luxe Greenville Retreat!
2 Mi to Downtown: Luxe Greenville Retreat!Greenville
"Great house! Very clean and comfortable. Outstanding amenities. Conveniently located. "
Cottage
Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Cozy Greenville Bungalow ~ 2 Mi to Downtown!Greenville
"Amazing place. Great host. "
Cottage
Stay at Jos Taylor Retreat: 9 Mi to Greenville!
Stay at Jos Taylor Retreat: 9 Mi to Greenville!Taylors
"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."
Cottage
Families Welcome, Fenced Yard: Inviting Greer Home
Families Welcome, Fenced Yard: Inviting Greer HomeGreer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Cottage
1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Cottage
Serene Cabin w/ Pond & Creek on South Saluda River
Serene Cabin w/ Pond & Creek on South Saluda RiverCleveland
"I chose this cabin due to its close proximity to the pretty place chapel. The property was BEAUTIFUL and tucked away. The silence and change of scenery was well needed and felt like we were at home. I honestly don’t have enough good things to say about the host Mr. Steve and his generosity and professionalism!"
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Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
Photo by Karyn Thompson
Fred W. Symmes Chapel
9.8/10 (29 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.
See all hotels in Upstate South Carolina
Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews
Drury Inn & Suites Greenville
10/10 Excellent
"Clean room and great staff breakfast and snacks were awesome"
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"Spacious room. Comfortable bed. Amazing buffet breakfast!"
Inn @ Clemson
8/10 Good
"Close to campus, staff was amazing, amenities were ehh, breakfast was small, gym was out of service."
The Shepherd Hotel Downtown Clemson
10/10 Excellent
"A truly refined and clean hotel!"
Comfort Suites At WestGate Mall
10/10 Excellent
"Staff were very professional and understanding. Very clean establishment. I would definitely come again, it was convenient to stores, and eateries."
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"Stayed during Clemson move in and it was great. Very reasonable price, clean room and good breakfast. Also super close to campus!"
Hyatt Place Greenville Downtown
8/10 Good
"I'd do it again. Great staff!"
Hotel Hartness
10/10 Excellent
"Amazing!"
Best Western Plus Greenville I-385 Inn & Suites
8/10 Good
"Checking in was odd because we booked ahead of time: but still required a card to check in. WiFi password was confusing until we figured out, beds were a little firm for my liking but the pillows were great. Room was clean and housekeeping was nice; parking kinda sucks tho. We didn’t eat the breakfast or use the pool/fitness center. We typically enjoyed our time in the city. But, it’s very centrally located to a lot, most things were only 10 mins away!"
More cheap stays in Upstate South Carolina
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
$59 nightly
$65 total
Aug 30 - Aug 31
Total with taxes and fees
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
$83 nightly
$91 total
Aug 30 - Aug 31
Total with taxes and fees
9.2/10 Wonderful! (1,562 reviews)
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
$89 nightly
$97 total
Aug 23 - Aug 24
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
161 Sha Ln Spartanburg SC
$95 nightly
$105 total
Aug 30 - Aug 31
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
$101 nightly
$112 total
Aug 20 - Aug 21
Total with taxes and fees
8/10 Very Good! (1,033 reviews)
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
$123 nightly
$135 total
Aug 19 - Aug 20
Total with taxes and fees
Hotels in Upstate South Carolina with star-rating
4 Star Hotels
30 properties
3 Star Hotels
196 properties
2 Star Hotels
145 properties
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- Hotels near Bon Secours Wellness Arena
- Hotels near Falls Park on the Reedy
- Greer Hotels
- Hotels with an Indoor Pool in Greenville
- Hotels with Free Airport Shuttle in Greenville - Spartanburg
- Hotels near Fluor Field at the West End
- Fountain Inn Hotels
- Pet-Friendly Hotels in Greenville
- Piedmont Hotels
- Clemson Hotels
- Hotels near Discovery Island Water Park
- Luxury Hotels in Greenville Downtown
- Romantic Hotels in Greenville
- Cabin Rentals in Upstate South Carolina
- Cheap Hotels in Greenville
- Hotels near The Shops at Greenridge
- Hotels near Haywood Mall
- Simpsonville Hotels
- Hotels near Greenville Technical College
- Hotels with an Indoor Pool in Upstate South Carolina
- Apartments in Greenville
- Hotels near Greenville Convention Center
- Hotels with Hot Tubs in Greenville
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- Romantic Hotels in Upstate South Carolina
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