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Find hotels in Upstate South Carolina, SC from $70
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Our top choices for Upstate South Carolina hotels
8.6 out of 10, Excellent, (425)
"Great place to stay"
Timothy
$78 nightly
The price is $85
Jan 5 - Jan 6, 2026
Total with taxes and fees
9.4 out of 10, Exceptional, (220)
"Great hotel. "
scott
$140 nightly
The price is $155
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.6 out of 10, Excellent, (1004)
"The staff was courteous in the room was spotless!"
Kimberly
$78 nightly
The price is $86
Jan 9 - Jan 10, 2026
Total with taxes and fees
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
Gene
$123 nightly
The price is $135
Dec 29 - Dec 30
Total with taxes and fees
9.2 out of 10, Wonderful, (1003)
"I have stayed here several times and it is always clean and comfortable, also the staff is very nice. "
Melissa
$122 nightly
The price is $134
Jan 4 - Jan 5, 2026
Total with taxes and fees
8.0 out of 10, Very Good, (665)
"Friendly check in, clean room."
connie
$79 nightly
The price is $87
Jan 4 - Jan 5, 2026
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cottage
9.8 out of 10, Exceptional, (9)
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Stay near popular Southeastern United States attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.
Photo by Michelle Hendrix
Open Photo by Michelle Hendrix
Top Upstate South Carolina Hotel Reviews
Homewood Suites by Hilton Greenville Downtown
10/10 Excellent
More cheap stays in Upstate South Carolina
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
$63 nightly
The price is $70 total per night from Dec 31 to Jan 1
$70 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
7.6/10 Good! (1,001 reviews)
Hotels in Upstate South Carolina with star-rating
4 Star Hotels
11 properties
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- Greenville Hotels
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