Title: Top 10 Hotels in Upstate South Carolina from $70 - Competitive Prices | Expedia.com [Upstate South Carolina Travel Guide](https://expedia.com/Upstate-South-Carolina.dx6057939)[Vacation Rentals in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Car Rentals in Upstate South Carolina](https://expedia.com/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.com/Upstate-South-Carolina.d6057939.Destination-Travel-Guides) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Upstate South Carolina Spa [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&amenities=SPA_ON_SITE) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&amenities=HOT_TUB) Pool [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&amenities=POOL) Great for families [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&travelerType=family_friendly) Pet-friendly [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&amenities=PETS) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&lodging=APARTMENT) Waterpark [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&amenities=WATER_PARK) Cottages [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&lodging=COTTAGE) Farm [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&lodging=AGRITOURISM) Resort [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&lodging=HOTEL_RESORT) Villas [](https://www.expedia.com/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-02-25&d1=2026-02-25&endDate=2026-02-27&d2=2026-02-27&lodging=VILLA) ## Check prices for these dates Tonight [Feb 11 - Feb 12](https://www.expedia.com/Hotel-Search?regionId=6057939&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 12 - Feb 13](https://www.expedia.com/Hotel-Search?regionId=6057939&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6057939&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6057939&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina hotels ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/fd542db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/a7c81686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/0689cad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/9b9d3bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Travelers Rest Greenville [](https://www.expedia.com/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) Travelers Rest 7.6/10 Good (1,000 reviews) "It was a pretty room. I only needed 1 night while visiting my son in the hospital. The employees were kind. The breakfast was decent. The bed and pillows felt amazing and the shower got nice and hot." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Molly $80 nightly $88 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/959a330b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/d217b18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cafe](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/893b2bfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Patrick Square [](https://www.expedia.com/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) Clemson 9.8/10 Exceptional (797 reviews) "Clean room, great location, wonderful staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joyce $149 nightly $165 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (563 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan $197 nightly $219 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27559/d19ba0e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27559/31acd213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking, Refrigerator & Microwave | Hypo-allergenic bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/27600/27559/4d6e6b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27600/27559/182e277c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Clemson-University Area [](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Clemson.h27559.Hotel-Information) Clemson 8.8/10 Excellent (628 reviews) "Was a clean, nice, convenient place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie $110 nightly $122 total Feb 18 - Feb 19 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Hampton-Inn-Clemson.h27559.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/60d71ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/330446c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Premium bedding, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/4f8e319f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/3e3a13ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clemson - University Area [](https://www.expedia.com/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) Clemson 8.2/10 Very Good (1,000 reviews) "Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delaney $97 nightly $108 total Feb 18 - Feb 19 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information) ![Golf](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/199642a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/0aec11f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson University's James F. Martin Inn [](https://www.expedia.com/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) Clemson 9.6/10 Exceptional (968 reviews) "Everything was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paige $149 nightly $165 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-f00c0668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-ce9cc597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center [](https://www.expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) Clemson 8.2/10 Very Good (1,002 reviews) "Our room was very clean and the staff were very nice and courteous!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina $91 nightly $101 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/ff716430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible (Mobility Accessible, Communications) | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/5d59466d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/w6000h3996x0y0-b212d0d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed (Low Floor) | Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558616/17641a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Clemson by IHG [](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) Clemson 8.8/10 Excellent (958 reviews) "Nice facility " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rishandrea $123 nightly $137 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Holiday-Inn-Express-Suites-Clemson.h2558616.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/462068d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/f1cbacdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/34438b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn @ Clemson [](https://www.expedia.com/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) Clemson 8.2/10 Very Good (1,005 reviews) "Staff and hotel was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keren $83 nightly $93 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Inn-Clemson.h84636.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/f08daaa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/d8583276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/7636779c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/a78c349a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Points by Sheraton Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) Spartanburg 9.4/10 Exceptional (450 reviews) "Friendly staff, clean rooms, excellent food! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley $119 nightly $132 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/7bf4f5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/62d6498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/d9e7f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356806/ff5159b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Spartanburg [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) Spartanburg 9.4/10 Exceptional (499 reviews) "Staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise $116 nightly $128 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hilton-Garden-Inn-Spartanburg.h31356806.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/dfd5de25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/8ef1c109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking (Efficiency) | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/edaae4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/26c9fcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport [](https://www.expedia.com/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) Greenville 8.4/10 Very Good (337 reviews) "everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Makiya $79 nightly $87 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/b1fdad7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/1b324965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/edb3bbb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Spartanburg Northwest [](https://www.expedia.com/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) Spartanburg 8.2/10 Very Good (831 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jamie $83 nightly $92 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/2fa8ed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/33c2ff7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/bd6af703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/290000/281700/281618/752d9078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Spartanburg-North I-85 [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) Spartanburg 8.6/10 Excellent (1,000 reviews) "Great staff, clean room, good location. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall $80 nightly $89 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Hampton-Inn-Spartanburg-North-I-85.h281618.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/0ab02d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/9b0a6f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/a2583d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, laptop workspace](https://images.trvl-media.com/lodging/119000000/118210000/118207900/118207809/ab207998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SUN AND SAND MOTEL [](https://www.expedia.com/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) Spartanburg 7.2/10 Good (15 reviews) "It was nice and cheap ...just wished my tv worked" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $63 nightly $70 total Feb 13 - Feb 14 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-SUN-AND-SAND-MOTEL.h118207809.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/1ada0475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/b84eb75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/36aa2afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2660000/2654400/2654329/9354fd9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites At WestGate Mall [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) Spartanburg 8.2/10 Very Good (1,000 reviews) "Easy to get in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas $95 nightly $105 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Comfort-Suites-At-WestGate-Mall.h2654329.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/4196fe01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/e6475e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/1dd9420f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel, BW Signature Collection [](https://www.expedia.com/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) Greenville 8.0/10 Very Good (957 reviews) "Clean comfortable room, excellent staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cyndi $59 nightly $65 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/97861c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/744c0880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/c3da6451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/910000/900200/900173/d3d5e3fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) Spartanburg 9.0/10 Wonderful (724 reviews) "Clean room, polite staff, great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna $107 nightly $119 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Spartanburg-Hotels-Holiday-Inn-Express-I-26-Us-29-At-Westgate-Mall.h900173.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/b55e4e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/c6ba3fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/59e05fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41970000/41964400/41964398/3a9e98a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville - Woodruff Road by IHG [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) Greenville 8.6/10 Excellent (674 reviews) "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candice $118 nightly $130 total Feb 15 - Feb 16 Total with taxes and fees [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Holiday-Inn-Woodruff-Road.h41964398.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (760 reviews) "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina $209 nightly $232 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_6057939) ## Vacation Rentals in Upstate South Carolina Cabin ![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/53271cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Queen Bed (View) | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/60991646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Seneca 9.8/10 Exceptional (58 reviews) "Excellent stay." [](https://www.expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) Cabin ![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin, 1 Bedroom, Courtyard View | Living area | 55-inch Smart TV with digital channels, streaming services](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/3f2de599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carolina Camp Cedar [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) Pickens 10/10 Exceptional (1 review) "This place was super clean and super cute! Convenient to everything I needed. I enjoyed the quietness." [](https://www.expedia.com/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information) Cottage ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/803858a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/55d24103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/02c27678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/db8f55c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### < 3 Mi to Dtwn: Modern Cottage in Greenville! [](https://www.expedia.com/Greenville-Hotels-3-Mi-To-Dtwn-Modern-Cottage-In-Greenville.h111929202.Hotel-Information) Greenville 10/10 Exceptional (1 review) [](https://www.expedia.com/Greenville-Hotels-3-Mi-To-Dtwn-Modern-Cottage-In-Greenville.h111929202.Hotel-Information) Aparthotel ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area | Smart TV](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Travelers Rest 10/10 Exceptional (16 reviews) "great place perfect for more privacy vs. a standard hotel" [](https://www.expedia.com/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Aparthotel ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/61217476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/464c71ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/002ffe20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Greenville-Haywood Mall [](https://www.expedia.com/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Greenville 9.0/10 Wonderful (202 reviews) "Room was very clean and welcoming. The only staff we met was Mark, and he was absolutely wonderful and friendly. " [](https://www.expedia.com/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) Apartment ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/d192b91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom (Self Check-in with Virtual Front Desk) | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/21618793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville Downtown by Kasa [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (792 reviews) "Spotless wonderful stay" [](https://www.expedia.com/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Cottage ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/b9728109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/8108d915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/8b275f49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/91d5d964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Claires Cottage \~ 4 Mi to Downtown Greenville! [](https://www.expedia.com/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information) Greenville 10/10 Exceptional (1 review) "Great trip. The small cottage was perfect for my wife and I and the owner was very responsive." [](https://www.expedia.com/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information) Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/ce6330d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/1cbd1706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/925daccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/6f31060d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Updated Greenville Home w/ Backyard! [](https://www.expedia.com/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information) Greenville 10/10 Exceptional (2 reviews) [](https://www.expedia.com/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information) Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/784635bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/e4c6187d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/09b84ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/6c10521c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Seneca Cabin \~ 4 Mi to Boat Launch! [](https://www.expedia.com/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information) Seneca 10/10 Exceptional (1 review) "Beautiful and quaint cabin! Highly recommend, great view of the lake." [](https://www.expedia.com/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/83f2467b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/9010a905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/1cae0fc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/72e7e252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 8 Mi to Clemson: Peaceful Family Home w/ Yard [](https://www.expedia.com/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information) Seneca 10/10 Exceptional (1 review) "The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much." [](https://www.expedia.com/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information) Cottage ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/e34f879b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/4964e86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/664f7ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/4f3ec318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 9 Mi to Devils Fork State Park: Getaway w/ Porch! [](https://www.expedia.com/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information) Tamassee 10/10 Exceptional (1 review) "Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!" [](https://www.expedia.com/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/89d76ac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/506b693f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/1b10d271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/3e1d7748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Lake Hartwell Vacation Rental w/ Dock! [](https://www.expedia.com/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information) Townville 10/10 Exceptional (1 review) [](https://www.expedia.com/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/53bf320b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/dc73b5c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/ea0ddd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94510000/94502500/94502491/8c0f98dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront South Carolina Abode w/ Deck & Boat Dock [](https://www.expedia.com/Waterfront-Lake-Hartwell-Cabin-Wdock-Near-Clemson.h94502491.Hotel-Information) Fair Play 9.0/10 Wonderful (2 reviews) "clean room, family friendly " [](https://www.expedia.com/Waterfront-Lake-Hartwell-Cabin-Wdock-Near-Clemson.h94502491.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/309d8bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/ebe19f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/86d9c4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/34ff4e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deck, Grill & Dock Access: Lake Keowee Retreat! [](https://www.expedia.com/Seneca-Hotels-Deck.h113184450.Hotel-Information) Seneca 10/10 Exceptional (1 review) "The best, perfect " [](https://www.expedia.com/Seneca-Hotels-Deck.h113184450.Hotel-Information) Cottage ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/2dac4e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/d3f21d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/0975de8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/c3510f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Greenville Bungalow \~ 2 Mi to Downtown! [](https://www.expedia.com/Greenville-Hotels-Cozy-Greenville-Bungalow-2-Mi-To-Downtown.h93537102.Hotel-Information) Greenville 8.0/10 Very Good (3 reviews) "Amazing place. Great host. " [](https://www.expedia.com/Greenville-Hotels-Cozy-Greenville-Bungalow-2-Mi-To-Downtown.h93537102.Hotel-Information) [See all vacation rentals](https://expedia.com/Hotel-Search?startDate=2026-03-11&endDate=2026-03-14®ionId=6057939&adults=2&sort=RECOMMENDED&stay_options_group=vacation_rentals_option&categorySearch=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels) ## Stay near popular Southeastern United States attractions !["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg) ### Clemson University 4.7/5 (738 reviews) Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6127431) ![Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views](https://images.trvl-media.com/place/6082697/4d276125-b8b6-4bd4-9887-c71157164970.jpg) ### Falls Park on the Reedy 4.7/5 (1,399 reviews) Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082697) ### Bon Secours Wellness Arena 4.2/5 (601 reviews) Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082715) ### Haywood Mall 4.3/5 (952 reviews) During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6130785) ### Memorial Stadium 4.7/5 (201 reviews) Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6193935) ### BMW Performance Center 4.7/5 (50 reviews) You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6217409) ## Learn more about Upstate South Carolina Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park. [See all hotels in Upstate South Carolina](https://www.expedia.com/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27&adults=2®ionId=6057939) ![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Visit Greenville, South Carolina ## Top Upstate South Carolina Hotel Reviews ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything was awesome!!!! " [](https://expedia.com/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "It is a really great location and we enjoyed our room." [](https://expedia.com/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Beautiful as soon you walk in and the rooms were great. Great location. " [](https://expedia.com/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "A dream come true since I was young to stay here. It truly was a lovely Christmas Eve. " [](https://expedia.com/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "The room was clean and the staff was friendly!" [](https://expedia.com/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Yes" [](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "great location, wonderful staff, delicious food" [](https://expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Excellent breakfast n ambience " [](https://expedia.com/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Room was very clean & the front desk staff were wonderful. So welcoming and polite!" [](https://expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ## More cheap stays in Upstate South Carolina ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Anderson 1007 George Smith Mill Rd Anderson SC $63 nightly $70 total Feb 15 - Feb 16 Total with taxes and fees 7.8/10 Good! (1,007 reviews) [](https://expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Greenville I-385 Inn & Suites 831 Congaree Rd Greenville SC $69 nightly $76 total Feb 15 - Feb 16 Total with taxes and fees 9/10 Wonderful! (1,433 reviews) [](https://expedia.com/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd](https://images.trvl-media.com/lodging/1000000/210000/202200/202137/b07dd898_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd 1024 Woodruff Rd Greenville SC $69 nightly $76 total Mar 1 - Mar 2 Total with taxes and fees 8.2/10 Very Good! (1,001 reviews) [](https://expedia.com/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h202137.Hotel-Information) ![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Seneca Clemson Area US-123 226 Hi Tech Rd Seneca SC $84 nightly $92 total Feb 18 - Feb 19 Total with taxes and fees 8/10 Very Good! (676 reviews) [](https://expedia.com/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information) ![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ECHO Suites Extended Stay by Wyndham Spartanburg 490 W Blackstock Road Spartanburg SC $84 nightly $95 total Feb 17 - Feb 18 Total with taxes and fees 8.2/10 Very Good! (341 reviews) [](https://expedia.com/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Clemson Hotel & Conference Center 1310 Tiger Blvd Clemson SC $91 nightly $101 total Feb 15 - Feb 16 Total with taxes and fees 8.2/10 Very Good! (1,002 reviews) [](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ## Hotels in Upstate South Carolina with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 11 properties [](https://expedia.com/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 194 properties [](https://expedia.com/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 316 properties [](https://expedia.com/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Greenville Hotels ](https://www.expedia.com/Greenville-Hotels.d1388.Travel-Guide-Hotels) - 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Center for Automotive Research ](https://www.expedia.com/CU-Intl-Center-For-Automotive-Research-Greenville.d6292800.Vacation-Attraction) - [Discovery Island Water Park ](https://www.expedia.com/Discovery-Island-Water-Park-Greenville.d553248621532656705.Vacation-Attraction) - [Terrace Shopping Center ](https://www.expedia.com/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction) - [Gatlin Park ](https://www.expedia.com/Gatlin-Park-Greenville.d553248621563220414.Vacation-Attraction) - [Golden Lanes and Golden Skate ](https://www.expedia.com/Golden-Lanes-And-Golden-Skate-Simpsonville.d553248621532656706.Vacation-Attraction) - [Rockwood Park ](https://www.expedia.com/Rockwood-Park-Greenville.d553248621563220415.Vacation-Attraction) - [Frankie's Fun Park ](https://www.expedia.com/Frankies-Fun-Park-Greenville.d553248621532656780.Vacation-Attraction) - [Gravitopia Trampoline Arena ](https://www.expedia.com/Gravitopia-Trampoline-Arena-Greenville.d553248621561867912.Vacation-Attraction) - [Green Forest Park ](https://www.expedia.com/Green-Forest-Park-Greenville.d553248621563220416.Vacation-Attraction) - [Car rental Greenville Airport (GDC) ](https://www.expedia.com/Car-Rentals-In-Donaldson-Center.d6309556.Car-Rental-Guide) - [Car rentals near Mauldin ](https://www.expedia.com/Car-Rentals-In-Mauldin.d183944.Car-Rental-Guide) - [Minivan Car Rentals in Mauldin ](https://www.expedia.com/Minivan-Car-Rentals-In-Mauldin.d183944-tMinivan.Car-Rental-Guide-Class) - [Enterprise Rental Cars in Mauldin ](https://www.expedia.com/Enterprise-Car-Rentals-In-Mauldin.d183944-c15.Car-Rental-Guide-Suppliers) - [Car rentals near Gantt ](https://www.expedia.com/Car-Rentals-In-Gantt.d553248634999376437.Car-Rental-Guide) - [Car rentals near Augusta Road Park ](https://www.expedia.com/Car-Rentals-In-Augusta-Road-Park.d553248621532656704.Car-Rental-Guide) - [Car rentals near Greenville ](https://www.expedia.com/Car-Rentals-In-Greenville.d1388.Car-Rental-Guide) - [Mauldin Vacation Rentals ](https://www.expedia.com/Mauldin-Vacation-Rentals.d183944.Travel-Guide-VacationRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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