Top 10 Hotels in Upstate South Carolina (from $62) 2026 - Competitive Prices

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Our top choices for Upstate South Carolina hotels

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

An indoor swimming pool with lounge chairs and potted plants.

A large hotel with a central courtyard, surrounded by manicured lawns and trees.

1. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

$108 nightly

$120 total

Oct 11 - Oct 12

Total with taxes and fees

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

A modern interior with a stone fireplace, seating areas, and a unique ceiling design.

A modern interior with a fireplace, plush seating, and a stone accent wall.

A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.

2. Grand Bohemian Lodge Greenville, Autograph Collection

Greenville Downtown

Michael

$401 nightly

$441 total

Oct 4 - Oct 5

Total with taxes and fees

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A fitness center with treadmills, elliptical machines, and a red exercise ball.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

3. Drury Inn & Suites Greenville

Greenville

Gohan

$115 nightly

$126 total

Nov 1 - Nov 2

Total with taxes and fees

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.

4. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

Roderick

$93 nightly

$103 total

Nov 1 - Nov 2

Total with taxes and fees

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A pool area with lounge chairs and a sign for Best Western Plus.

5. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

$76 nightly

$84 total

Oct 11 - Oct 12

Total with taxes and fees

A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

A bar with multiple shelves of liquor bottles and glasses hanging above.

A modern living room with a fireplace, seating area, and a bar with shelves of bottles.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

6. Hotel Hartness

Greenville

Kodjo

$208 nightly

$228 total

Oct 4 - Oct 5

Total with taxes and fees

A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

A modern living room with a fireplace, a flat-screen TV, and comfortable seating.

A reception area with two reception desks, a large cityscape poster, and a plant.

A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

7. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Greenville

Lissette

$105 nightly

$116 total

Oct 4 - Oct 5

Total with taxes and fees

A spacious lobby with modern furniture, a chandelier, and potted plants.

A bar with a white countertop, multiple bar stools, and shelves stocked with bottles.

8. Hilton Greenville

Greenville

Edward

$117 nightly

$129 total

Oct 18 - Oct 19

Total with taxes and fees

A spacious lobby with a central bar area, multiple seating options, and a distinctive ceiling structure.

A Hyatt Regency building with a modern facade, a landscaped entrance area, and a sign indicating the location.

An outdoor dining area with a fire feature and a wall with the word "ROOST" illuminated.

A courtyard with a fountain, potted plants, and directional signs for registration, valet parking, and self parking.

9. Hyatt Regency Greenville

Greenville Downtown

Rich

$174 nightly

$191 total

Nov 1 - Nov 2

Total with taxes and fees

A multi-story hotel with a modern design, featuring a mix of glass and brick facades, and a parking area with autumn-colored trees.

A modern hotel lobby with a mix of seating areas, including sofas and tables, and a patterned carpet.

A modern hotel lobby with a reception desk, seating area, and a decorative wall.

10. Hyatt Place Greenville Downtown

Greenville Downtown

Tamara

$134 nightly

$147 total

Oct 11 - Oct 12

Total with taxes and fees

A hotel entrance with a modern design, featuring a prominent 'aloft' sign, a covered walkway, and decorative lighting.

A modern cafe with a central counter, multiple seating areas, and large windows.

A rooftop patio with a fire pit surrounded by red chairs, a modern building in the background, and a clear sky.

A hotel room with a wooden desk, a blue chair, and a TV.

11. Aloft by Marriott Greenville Downtown

Greenville Downtown

Mark

$160 nightly

$176 total

Oct 11 - Oct 12

Total with taxes and fees

A multi-story hotel with a stone facade, large windows, and outdoor seating areas.

A hotel room with a patterned sofa, a round ottoman, a desk with a chair, a large mirror, and a television.

A spacious dining area with round tables and chairs, large windows with sheer curtains, and pendant lighting.

A modern building with a covered outdoor seating area and a sign reading "The Commons".

12. Hampton Inn & Suites Greenville-Downtown-RiverPlace

Greenville Downtown

James

$160 nightly

$176 total

Oct 25 - Oct 26

Total with taxes and fees

An outdoor patio area with a wooden pergola, barbecue grill, and seating.

A modern hotel lobby with a reception desk, a large round rug, a sofa, and a unique chandelier.

A modern hotel lobby with a seating area featuring sofas and round tables, large windows, and a decorative wooden panel.

A modern building with large windows and a brick facade at a street corner.

13. Homewood Suites by Hilton Greenville Downtown

Greenville Downtown

Michael

$151 nightly

$166 total

Oct 11 - Oct 12

Total with taxes and fees

A multi-story hotel with a modern design, featuring balconies, large windows, and a reflection in the water.

A modern lobby with a curved gray sectional sofa, a round black coffee table, and a patterned rug.

A spacious lobby with a round coffee table, patterned sofas, a large mirror, and a modern kitchen in the background.

A spacious restaurant with high ceilings, exposed beams, and large windows offering a view of the city. Tables are set with wine glasses and plates, ready for dining.

14. Embassy Suites by Hilton Greenville Downtown Riverplace

Greenville Downtown

Tom

$160 nightly

$177 total

Nov 1 - Nov 2

Total with taxes and fees

A modern kitchen with hanging light fixtures and bar seating.

A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern bar area with a central island, bar stools, and overhead lighting.

15. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jeffery

$118 nightly

$129 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.

A hotel room with a bed, a desk with a chair, a television, a window with curtains, and a bedside table with a lamp.

A modern kitchen with a granite countertop, a built-in grill, a microwave, and a coffee maker. There are two framed artworks on the wall and a refrigerator with a built-in ice maker.

A laundry room with two stacked washing machines and a single dryer.

16. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Greenville

Charles

$76 nightly

$83 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel facade with arched windows, a fountain, and a sign for "The Westin."

A grand lobby with a chandelier, multiple seating areas, and a checkered floor pattern.

A lobby with patterned flooring, a grand staircase, and elegant furniture.

17. The Westin Poinsett Greenville

Greenville Downtown

Karen

$176 nightly

$194 total

Oct 11 - Oct 12

Total with taxes and fees

An outdoor patio with a modern design, featuring a seating area with sofas and a fire pit, surrounded by plants and under a pergola with hanging lights.

A modern hotel lobby with a central seating area, a long reception desk, and a kitchen area visible to the right.

A modern office space with a wooden partition, two desks with computers, green chairs, and a glass door leading outside.

A modern interior with a bar area, seating, and a staircase.

18. SpringHill Suites by Marriott Greenville Downtown

Greenville Downtown

Douglas

$141 nightly

$155 total

Oct 11 - Oct 12

Total with taxes and fees

A modern lobby with a seating area, a large abstract painting, and a staircase.

A modern hotel room with two beds, a sofa, a small wooden table, and a large window.

A modern lobby with a grey sofa, yellow armchairs, a round table with fruit, and a large abstract painting.

19. Hyatt Place Greenville/Haywood

Greenville

Jonathan

$82 nightly

$91 total

Oct 18 - Oct 19

Total with taxes and fees

A spacious living area with a fireplace, a beige sofa, and a modern chandelier.

A multi-story hotel with a prominent entrance and a landscaped driveway.

A modern retail store named 'The Shop' with a variety of products including snacks, beverages, and household items.

A modern breakfast bar with wooden stools, a coffee station, and a variety of breakfast items.

20. Hilton Garden Inn Greenville

Greenville

Leroy

$106 nightly

$116 total

Oct 31 - Nov 1

Total with taxes and fees

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Vacation Rentals in Upstate South Carolina

Aparthotel

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A dining area with a wooden table set for two, a blue chair, a small table with a lamp, and a kitchen in the background.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A kitchen with a wooden countertop, a sink, a coffee maker, a toaster, and a window with a view of trees.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Aparthotel

A modern building with outdoor seating and a garden.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A wooden interior with a table, chair, and a hanging lantern.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

A wooden bridge leading to a playground with green grass and trees.

A backyard with a gazebo, a fire pit, and a covered seating area.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A two-story house with a front porch, a small garden, and a wooden fence.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Apartment

A large house with a spacious driveway and a pond in the background.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

A modern kitchen with a central island, wooden cabinets, and a dining area with bar stools.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A modern kitchen with white cabinets, stainless steel appliances, and a patterned rug.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A wooden deck with a bench and a welcome mat, overlooking a well-maintained lawn and trees.

A spacious living room with hardwood floors, a fireplace, a sofa, a coffee table, and a television.

A bedroom with a large bed, a ceiling fan, a TV, and a window with blinds.

A rustic cabin with a wooden deck, a covered patio, and a large window overlooking a wooded area.

Serene Cabin w/ Pond & Creek on South Saluda River

Cleveland

"I chose this cabin due to its close proximity to the pretty place chapel. The property was BEAUTIFUL and tucked away. The silence and change of scenery was well needed and felt like we were at home. I honestly don’t have enough good things to say about the host Mr. Steve and his generosity and professionalism!"

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent

"Very nice stay and conviennent"

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent

"Really a great stay ."

Lakeside Lodge Clemson

10/10 Excellent

"My first time here. Lovely resort. Pool was awesome. Poolside restaurant had good sandwiches. I wish the breakfast was open before 10:00 am, but the free coffee was nice. I walked to Starbucks for breakfast. Room was spacious."

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"clean room"

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"The room was very clean and comfortable. Staff was helpful and friendly. The lobby is to die for with the displays of Native American art and jewelry. A fun place e to stay with convenient location."

Comfort Inn & Suites Clemson - University Area

8/10 Good

"Great stay. Clean and conveniently located."

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

$76 nightly

$83 total

Nov 1 - Nov 2

Total with taxes and fees

8.4/10 Very Good! (1,001 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

$76 nightly

$84 total

Oct 11 - Oct 12

Total with taxes and fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

$89 nightly

$97 total

Oct 11 - Oct 12

Total with taxes and fees

8.2/10 Very Good! (1,003 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

$101 nightly

$112 total

Oct 4 - Oct 5

Total with taxes and fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

$109 nightly

$121 total

Nov 1 - Nov 2

Total with taxes and fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

$119 nightly

$131 total

Oct 4 - Oct 5

Total with taxes and fees

9/10 Wonderful! (1,001 reviews)

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia

Things to do in Upstate South Carolina

Find hotels in Upstate South Carolina, SC from $62

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Embassy Suites Greenville Golf Resort & Conference Center

2. Grand Bohemian Lodge Greenville, Autograph Collection

3. Drury Inn & Suites Greenville

4. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

5. Best Western Plus Greenville I-385 Inn & Suites

6. Hotel Hartness

7. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

8. Hilton Greenville

9. Hyatt Regency Greenville

10. Hyatt Place Greenville Downtown

11. Aloft by Marriott Greenville Downtown

12. Hampton Inn & Suites Greenville-Downtown-RiverPlace

13. Homewood Suites by Hilton Greenville Downtown

14. Embassy Suites by Hilton Greenville Downtown Riverplace

15. DoubleTree by Hilton Greenville Woodruff Road

16. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

17. The Westin Poinsett Greenville

18. SpringHill Suites by Marriott Greenville Downtown

19. Hyatt Place Greenville/Haywood

20. Hilton Garden Inn Greenville

Vacation Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

Claires Cottage ~ 4 Mi to Downtown Greenville!

Carolina Camp Cedar

The Station by Compo Hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Carolina Landing RV Resort - Caravan Park

Clemson Memorabilia House

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greer Guest House < 1 Mi to Park & Downtown Area!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Serene Cabin w/ Pond & Creek on South Saluda River

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Lakeside Lodge Clemson

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Grand Bohemian Lodge Greenville, Autograph Collection

Comfort Inn & Suites Clemson - University Area

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating

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